This important volume is the first comprehensive text in two decades on central pain syndromes. Leading scientists and clinicians review the latest findings and theories on the pathophysiology of central pain, describe the clinical characteristics of central pain in stroke and spinal cord injury patients, assess the efficacy of opioids and other pharmacologic agents in relieving central pain, and explore potential new therapies such as transcutaneous electrical nerve stimulation (TENS), central nervous system stimulation, and ablative procedures. The contributors also describe various psychometric and neurophysiological approaches to measuring and assessing central pain.